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Longevity & Neuro Research

Research Use Only — Not for Human or Veterinarian Administration

Fox-04 (10mg)

FOXO4-DRI is a D-retro-inverso peptide designed to disrupt the FOXO4-p53 interaction in senescent cells, investigated as a senolytic agent in aging and cellular senescence research.

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lyophilized

$99.00/ Fox-04 (10mg)

Certificate of AnalysisThird-party HPLC lab report · opens PDF

For laboratory and research use only. Not for human or veterinary use.

Mechanism of Action

The D-retro-inverso modification confers protease resistance. The peptide competitively interferes with FOXO4-p53 binding, selectively inducing apoptosis in senescent cells while sparing proliferating cells in preclinical models.

Research Applications

Cellular senescence and senolytic assays
FOXO4-p53 interaction studies
Aging and tissue rejuvenation research models

Specifications

sequence	D-retro-inverso FOXO4-p53 interfering peptide
molecular Weight	~5350 Da
appearance	White lyophilized powder

Reconstitution (Laboratory)

Reconstitute with bacteriostatic water. Handle as a sensitive research peptide.

Storage & Handling

Lyophilized: −20 °C recommended for long-term. Reconstituted: refrigerate; use promptly.

Quality Assurance

Every lot undergoes independent third-party HPLC purity analysis, mass spectrometry identity confirmation, and endotoxin testing (<0.5 EU/mg). Certificate of Analysis (COA) is stored against the SKU lot number and available through your research account portal.