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GHK-Cu (100mg)
Recovery & Tissue Research
Research Use Only — Not for Human or Veterinarian Administration

GHK-Cu (100mg)

GHK-Cu (glycyl-L-histidyl-L-lysine copper complex) is a naturally occurring tripeptide-copper complex first characterized in human plasma. It is widely studied in laboratory models of collagen synthesis, wound repair, and gene expression modulation.

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lyophilized
$55.00/ GHK-Cu (100mg)
Certificate of Analysis — GHK-Cu (100mg)Certificate of AnalysisThird-party HPLC lab report · opens PDF

For laboratory and research use only. Not for human or veterinary use.

Mechanism of Action

GHK-Cu delivers copper as a cofactor for lysyl oxidase and antioxidant enzymes. Research indicates modulation of genes involved in tissue remodeling, anti-inflammatory signaling, and extracellular matrix production.

Research Applications

  • Collagen and ECM synthesis assays
  • Wound-healing and fibroblast proliferation models
  • Skin remodeling and hair follicle research
  • Copper-mediated antioxidant pathway studies

Specifications

sequenceGly-His-Lys (Cu²⁺ complex)
molecular Weight340.38 Da (peptide); 403.92 Da (Cu complex)
cas49557-75-7
appearanceBlue-tinted lyophilized powder when copper-bound

Reconstitution (Laboratory)

Add bacteriostatic water under sterile conditions. Solution may exhibit a blue color indicating copper coordination — this is expected. Concentration depends on protocol requirements.

Storage & Handling

Lyophilized: 2–8 °C recommended. Reconstituted: refrigerate; protect from light. Copper complexes are sensitive to oxidation — use appropriate laboratory handling.

Quality Assurance

Every lot undergoes independent third-party HPLC purity analysis, mass spectrometry identity confirmation, and endotoxin testing (<0.5 EU/mg). Certificate of Analysis (COA) is stored against the SKU lot number and available through your research account portal.

Sources & References

  1. 1.Pickart L, Margolina A. Regenerative and protective actions of the GHK-Cu peptide. Int J Mol Sci. 2018. · PubMed →
  2. 2.Pickart L. The human tri-peptide GHK and tissue remodeling. J Biomater Sci Polym Ed. 2008. · PubMed →
  3. 3.Maquart FX, et al. In vivo stimulation of collagen synthesis in animal skin. FEBS Lett. 1993. · PubMed →