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GLP-2
Metabolic Research
Research Use Only — Not for Human or Veterinarian Administration

GLP-2

GLP-2 is an intestinal growth factor peptide studied for its trophic effects on the GI mucosa, nutrient absorption, and gut barrier function in research models.

Select size

lyophilized
$150.00/ 30mg
Certificate of Analysis — GLP-2Certificate of AnalysisThird-party HPLC lab report · opens PDF

For laboratory and research use only. Not for human or veterinary use.

Mechanism of Action

GLP-2 acts via the GLP-2 receptor (GLP2R) expressed on intestinal enteroendocrine cells, promoting crypt cell proliferation, reducing apoptosis, and enhancing barrier integrity in preclinical models.

Research Applications

  • Intestinal mucosal growth assays
  • Gut barrier permeability research
  • Short bowel syndrome model studies
  • Nutrient absorption pathway research

Specifications

sequenceGLP-2 analogue
molecular Weight~3.9 kDa (native GLP-2)
appearanceWhite lyophilized powder

Reconstitution (Laboratory)

Reconstitute with bacteriostatic water per protocol. Verify mass against COA.

Storage & Handling

Lyophilized: 2–8 °C for extended storage. Reconstituted: refrigerate at 2–8 °C.

Quality Assurance

Every lot undergoes independent third-party HPLC purity analysis, mass spectrometry identity confirmation, and endotoxin testing (<0.5 EU/mg). Certificate of Analysis (COA) is stored against the SKU lot number and available through your research account portal.

Sources & References

  1. 1.Drucker DJ, et al. Discovery, characterization, and clinical development of the glucagon-like peptides. J Clin Invest. 2017. · PubMed →
  2. 2.Jeppesen PB. Clinical significance of GLP-2 in short-bowel syndrome. J Nutr. 2003. · PubMed →