GLP-1

GLP-1 (glucagon-like peptide-1) receptor agonist analogues are central to metabolic research, modulating incretin signaling, glucose-dependent insulin secretion, and gastric motility in laboratory models.

Select size

lyophilized

$95.00/ 10mg

Certificate of AnalysisThird-party HPLC lab report · opens PDF

For laboratory and research use only. Not for human or veterinary use.

Mechanism of Action

GLP-1 analogues bind the GLP-1 receptor (GLP1R), activating cAMP/PKA pathways in pancreatic beta cells and central appetite-regulating circuits. Research focuses on receptor binding kinetics, downstream signaling, and metabolic endpoint assays.

Research Applications

Incretin pathway and GLP1R binding assays
Glucose homeostasis research models
Appetite and satiety signaling studies
Gastric emptying and GI motility research

Specifications

sequence	GLP-1 analogue (sequence varies by modification)
molecular Weight	Varies by analogue (~3–4 kDa typical)
appearance	White lyophilized powder

Reconstitution (Laboratory)

Use bacteriostatic water under sterile laboratory conditions. Peptide concentration should be calculated per vial mass and verified against COA.

Storage & Handling

Lyophilized: stable for shipping at ambient temperature; long-term storage at 2–8 °C. Reconstituted: refrigerate immediately; minimize freeze-thaw cycles.

Quality Assurance

Every lot undergoes independent third-party HPLC purity analysis, mass spectrometry identity confirmation, and endotoxin testing (<0.5 EU/mg). Certificate of Analysis (COA) is stored against the SKU lot number and available through your research account portal.